Proteases

RENIN

Recombinant ID:

3936

Gene of Interest

Gene Synonyms:

REN

Protein Names:

Renin (EC 3.4.23.15) (Angiotensinogenase)

Accession Data

Organism:

Homo sapiens (Human)

Mass (kDa):

45057

Length (aa):

406

Proteomics (Proteome ID):

Renin (EC 3.4.23.15) (Angiotensinogenase)

Proteomics (Chromosome):

UP000005640

Sequence:

MDGWRRMPRWGLLLLLWGSCTFGLPTDTTTFKRIFLKRMPSIRESLKERGVDMARLGPEWSQPMKRLTLGNTTSSVILTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITVTQMFGEVTEMPALPFMLAEFDGVVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDSENSQSLGGQIVLGGSDPQHYEGNFHYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISGSTSSIEKLMEALGAKKRLFDYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSSKKLCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDRRNNRIGFALAR

Analysis Summary:

Active site (2); Alternative sequence (1); Beta strand (29); Chain (1); Disulfide bond (3); Domain (1); Glycosylation (2); Helix (14); Natural variant (6); Propeptide (1); Sequence conflict (4); Signal peptide (1); Turn (5),N/A,N/A,N/A,N/A,N/A,N/A,Renal tubular dysgenesis (RTD) [MIM:267430]: Autosomal recessive severe disorder of renal tubular development characterized by persistent fetal anuria and perinatal death, probably due to pulmonary hypoplasia from early-onset oligohydramnios (the Potter phenotype). {ECO:0000269|PubMed:16116425}. Note=The disease is caused by mutations affecting the gene represented in this entry.; Familial juvenile hyperuricemic nephropathy 2 (HNFJ2) [MIM:613092]: A renal disease characterized by juvenile onset of hyperuricemia, slowly progressive renal failure and anemia. {ECO:0000269|PubMed:19664745}. Note=The disease is caused by mutations affecting the gene represented in this entry.

Reagent Data

Name:

Renin (EC 3.4.23.15) (Angiotensinogenase)

Subcategory:

Recombinant

 Molecular Weight:

43.2 kDa

Source:

HEK293

Species:

Human

Tag:

Format:

Lyophilized

pH:

7.4-7.5

Formulation:

Sterile-filtered colorless solution

Formulation Concentration:

1mg/ml

Buffer Volume:

Standard

Buffer Solution:

PBS

Metal Chelating Agents

Purity:

> 98%

Determined:

SDS-PAGE

Validated:

RP-HPLC

Sample Handling

Storage:

-20°C

Stability:

This bioreagent is stable at 4°C (short-term) and -70°C(long-term). After reconstitution, sample may be stored at 4°C for 2-7 days and below -18°C for future use.

Preparation:

Reconstitute in sterile distilled H2O to no less than 100ug/ml; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance.
Share by: