Cytokines

LIF

Recombinant ID:

3626

Gene of Interest

Gene Synonyms:

LIF;HILDA

Protein Names:

Leukemia inhibitory factor (LIF) (Differentiation-stimulating factor) (D factor) (Melanoma-derived LPL inhibitor) (MLPLI) (Emfilermin)

Accession Data

Organism:

Homo sapiens (Human)

Mass (kDa):

22008

Length (aa):

202

Proteomics (Proteome ID):

Leukemia inhibitory factor (LIF) (Differentiation-stimulating factor) (D factor) (Melanoma-derived LPL inhibitor) (MLPLI) (Emfilermin)

Proteomics (Chromosome):

UP000005640

Sequence:

MKVLAAGVVPLLLVLHWKHGAGSPLPITPVNATCAIRHPCHNNLMNQIRSQLAQLNGSANALFILYYTAQGEPFPNNLDKLCGPNVTDFPPFHANGTEKAKLVELYRIVVYLGTSLGNITRDQKILNPSALSLHSKLNATADILRGLLSNVLCRLCSKYHVGHVDVTYGPDTSGKDVFQKKKLGCQLLGKYKQIIAVLAQAF

Analysis Summary:

LIF has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes.,Alternative sequence (2); Beta strand (2); Chain (1); Disulfide bond (3); Glycosylation (6); Helix (5); Signal peptide (1); Turn (1)

Reagent Data

Name:

Leukemia inhibitory factor (LIF) (Differentiation-stimulating factor) (D factor) (Melanoma-derived LPL inhibitor) (MLPLI) (Emfilermin)

Subcategory:

Recombinant

Amino Acid Sequence:

Inquire

Species

Human

Tag:

Format:

Lyophilized

pH:

7.4-7.5

Formulation:

Sterile-filtered colorless solution

Buffer Volume

Standard

Buffer Solution:

PBS

Metal Chelating Agents

Purity:

> 98%

Determined:

SDS-PAGE

Stained:

Assay (Variable)

Validated:

RP-HPLC

Sample Handling

Storage:

-20°C

Stability:

This bioreagent is stable at 4°C (short-term) and -70°C(long-term). After reconstitution, sample may be stored at 4°C for 2-7 days and below -18°C for future use.

Preparation:

Reconstitute in sterile distilled H2O to no less than 100ug/ml; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance.

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