Cytokines

IL-2

Recombinant ID:

3615

Gene of Interest

Gene Synonyms:

IL2

Protein Names:

Interleukin-2 (IL-2) (T-cell growth factor) (TCGF) (Aldesleukin)

Accession Data

Organism:

Homo sapiens (Human)

Mass (kDa):

17628

Length (aa):

153

Proteomics (Proteome ID):

Interleukin-2 (IL-2) (T-cell growth factor) (TCGF) (Aldesleukin)

Proteomics (Chromosome):

UP000005640

Sequence:

MYRMQLLSCIALSLALVTNSAPTSSSTKKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPKKATELKHLQCLEEELKPLEEVLNLAQSKNFHLRPRDLISNINVIVLELKGSETTFMCEYADETATIVEFLNRWITFCQSIISTLT

Analysis Summary:

Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells.,Beta strand (3); Chain (1); Disulfide bond (1); Erroneous initiation (1); Glycosylation (1); Helix (8); Natural variant (2); Signal peptide (1); Turn (2),Note=A chromosomal aberration involving IL2 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with involves TNFRSF17. {ECO:0000269|PubMed:1396583}.

Reagent Data

Name:

Interleukin-2 (IL-2) (T-cell growth factor) (TCGF) (Aldesleukin)

Subcategory:

Recombinant

Amino Acid Sequence:

Inquire

Species

Human

Tag:

Format:

Lyophilized

pH:

7.4-7.5

Formulation:

Sterile-filtered colorless solution

Buffer Volume

Standard

Buffer Solution:

PBS

Metal Chelating Agents

Purity:

> 98%

Determined:

SDS-PAGE

Stained:

Assay (Variable)

Validated:

RP-HPLC

Sample Handling

Storage:

-20°C

Stability:

This bioreagent is stable at 4°C (short-term) and -70°C(long-term). After reconstitution, sample may be stored at 4°C for 2-7 days and below -18°C for future use.

Preparation:

Reconstitute in sterile distilled H2O to no less than 100ug/ml; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance.

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