Cytokines
IL-17A
Recombinant ID:
3612
Gene of Interest
Gene Synonyms:
Il17a;Ctla8;Il17
Protein Names:
Interleukin-17A (IL-17) (IL-17A) (Cytotoxic T-lymphocyte-associated antigen 8) (CTLA-8)
Accession Data
Organism:
Mus musculus (Mouse)
Mass (kDa):
17490
Length (aa):
158
Proteomics (Proteome ID):
Interleukin-17A (IL-17) (IL-17A) (Cytotoxic T-lymphocyte-associated antigen 8) (CTLA-8)
Proteomics (Chromosome):
UP000000589
Sequence:
MSPGRASSVSLMLLLLLSLAATVKAAAIIPQSSACPNTEAKDFLQNVKVNLKVFNSLGAKVSSRRPSDYLNRSTSPWTLHRNEDPDRYPSVIWEAQCRHQRCVNAEGKLDHHMNSVLIQQEILVLKREPESCPFTFRVEKMLVGVGCTCVASIVRQAA
Analysis Summary:
Ligand for IL17RA (PubMed:17911633). The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC (By similarity). Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines (By similarity). {ECO:0000250|UniProtKB:Q16552, ECO:0000269|PubMed:17911633}.,Chain (1); Disulfide bond (2); Glycosylation (1); Signal peptide (1),Induced upon antigen receptor ligation in the presence of IL6 and TGB1. {ECO:0000269|PubMed:16990136}.,Restricted to a subset of activated T-cells. {ECO:0000269|PubMed:16990136}.
Reagent Data
Name:
Interleukin-17A (IL-17) (IL-17A) (Cytotoxic T-lymphocyte-associated antigen 8) (CTLA-8)
Subcategory:
Recombinant
Amino Acid Sequence:
Inquire
Species
Mouse
Tag:
Format:
Lyophilized
pH:
7.4-7.5
Formulation:
Sterile-filtered colorless solution
Buffer Volume
Standard
Buffer Solution:
PBS
Metal Chelating Agents
Purity:
> 98%
Determined:
SDS-PAGE
Stained:
Assay (Variable)
Validated:
RP-HPLC
Sample Handling
Storage:
-20°C
Stability:
This bioreagent is stable at 4°C (short-term) and -70°C(long-term). After reconstitution, sample may be stored at 4°C for 2-7 days and below -18°C for future use.
Preparation:
Reconstitute in sterile distilled H2O to no less than 100ug/ml; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance.
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