Cytokines

IL-1 alpha

Recombinant ID:

3601

Gene of Interest

Gene Synonyms:

IL1A;IL1F1

Protein Names:

Interleukin-1 alpha (IL-1 alpha) (Hematopoietin-1)

Accession Data

Organism:

Homo sapiens (Human)

Mass (kDa):

30607

Length (aa):

271

Proteomics (Proteome ID):

Interleukin-1 alpha (IL-1 alpha) (Hematopoietin-1)

Proteomics (Chromosome):

UP000005640

Sequence:

MAKVPDMFEDLKNCYSENEEDSSSIDHLSLNQKSFYHVSYGPLHEGCMDQSVSLSISETSKTSKLTFKESMVVVATNGKVLKKRRLSLSQSITDDDLEAIANDSEEEIIKPRSAPFSFLSNVKYNFMRIIKYEFILNDALNQSIIRANDQYLTAAALHNLDEAVKFDMGAYKSSKDDAKITVILRISKTQLYVTAQDEDQPVLLKEMPEIPKTITGSETNLLFFWETHGTKNYFTSVAHPNLFIATKQDYWVCLAGGPPSITDFQILENQA

Analysis Summary:

Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.,Beta strand (18); Chain (1); Glycosylation (2); Helix (2); Lipidation (2); Modified residue (1); Natural variant (5); Propeptide (1)

Reagent Data

Name:

Interleukin-1 alpha (IL-1 alpha) (Hematopoietin-1)

Subcategory:

Recombinant

Amino Acid Sequence:

Inquire

Species

Human

Tag:

Format:

Lyophilized

pH:

7.4-7.5

Formulation:

Sterile-filtered colorless solution

Buffer Volume

Standard

Buffer Solution:

PBS

Metal Chelating Agents

Purity:

> 98%

Determined:

SDS-PAGE

Stained:

Assay (Variable)

Validated:

RP-HPLC

Sample Handling

Storage:

-20°C

Stability:

This bioreagent is stable at 4°C (short-term) and -70°C(long-term). After reconstitution, sample may be stored at 4°C for 2-7 days and below -18°C for future use.

Preparation:

Reconstitute in sterile distilled H2O to no less than 100ug/ml; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance.

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