Cytokines

IFN-gamma

Recombinant ID:

3600

Gene of Interest

Gene Synonyms:

IFNG

Protein Names:

Interferon gamma (IFN-gamma) (Immune interferon)

Accession Data

Organism:

Homo sapiens (Human)

Mass (kDa):

19348

Length (aa):

166

Proteomics (Proteome ID):

Interferon gamma (IFN-gamma) (Immune interferon)

Proteomics (Chromosome):

UP000005640

Sequence:

MKYTSYILAFQLCIVLGSLGCYCQDPYVKEAENLKKYFNAGHSDVADNGTLFLGILKNWKEESDRKIMQSQIVSFYFKLFKNFKDDQSIQKSVETIKEDMNVKFFNSNKKKRDDFEKLTNYSVTDLNVQRKAIHELIQVMAELSPAAKTGKRKRSQMLFRGRRASQ

Analysis Summary:

Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.,Chain (1); Glycosylation (2); Helix (9); Modified residue (1); Natural variant (2); Propeptide (1); Signal peptide (1); Turn (1),Released primarily from activated T lymphocytes.,Aplastic anemia (AA) [MIM:609135]: A form of anemia in which the bone marrow fails to produce adequate numbers of peripheral blood elements. It is characterized by peripheral pancytopenia and marrow hypoplasia. {ECO:0000269|PubMed:15327519}. Note=Disease susceptibility may be associated with variations affecting the gene represented in this entry.

Reagent Data

Name:

Interferon gamma (IFN-gamma) (Immune interferon)

Subcategory:

Recombinant

Amino Acid Sequence:

Inquire

Species

Human

Tag:

Format:

Lyophilized

pH:

7.4-7.5

Formulation:

Sterile-filtered colorless solution

Buffer Volume

Standard

Buffer Solution:

PBS

Metal Chelating Agents

Purity:

> 98%

Determined:

SDS-PAGE

Stained:

Assay (Variable)

Validated:

RP-HPLC

Sample Handling

Storage:

-20°C

Stability:

This bioreagent is stable at 4°C (short-term) and -70°C(long-term). After reconstitution, sample may be stored at 4°C for 2-7 days and below -18°C for future use.

Preparation:

Reconstitute in sterile distilled H2O to no less than 100ug/ml; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance.
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