Biomarkers
SECTM1
Recombinant ID:
3541
Gene of Interest
Gene Synonyms:
SECTM1;K12
Protein Names:
Secreted and transmembrane protein 1 (Protein K-12)
Accession Data
Organism:
Homo sapiens (Human)
Mass (kDa):
27039
Length (aa):
248
Metal Binding:
Pending Verification
Proteomics (Proteome ID):
Secreted and transmembrane protein 1 (Protein K-12)
Proteomics (Chromosome):
UP000005640
Disease:
N/A
Mutagenesis:
N/A
Sequence:
MQTCPLAFPGHVSQALGTLLFLAASLSAQNEGWDSPICTEGVVSVSWGENTVMSCNISNAFSHVNIKLRAHGQESAIFNEVAPGYFSRDGWQLQVQGGVAQLVIKGARDSHAGLYMWHLVGHQRNNRQVTLEVSGAEPQSAPDTGFWPVPAVVTAVFILLVALVMFAWYRCRCSQQRREKKFFLLEPQMKVAALRAGAQQGLSRASAELWTPDSEPTPRPLALVFKPSPLGALELLSPQPLFPYAADP
Function [CC]:
May be involved in thymocyte signaling. {ECO:0000269|PubMed:15742156}.
Analysis Summary:
Chain (1); Disulfide bond (1); Glycosylation (1); Sequence conflict (1); Signal peptide (1); Topological domain (2); Transmembrane (1); By IFNG/IFN-gamma (at protein level). {ECO:0000269|PubMed:15742156}.; Detected at the highest levels in peripheral blood leukocytes and breast cancer cell lines. Found in leukocytes of the myeloid lineage, with the strongest expression observed in granulocytes and no detectable expression in lymphocytes. Expressed in thymic epithelial cells and fibroblasts. {ECO:0000269|PubMed:15742156, ECO:0000269|PubMed:9480746}.
Reagent Data
Name:
Secreted and transmembrane protein 1 (Protein K-12)
Subcategory:
Recombinant
Source:
HEK293
Species:
Format:
Lyophilized
pH:
7.4-7.5
Formulation:
Sterile-filtered colorless solution
Formulation Concentration:
1mg/ml
Buffer Volume:
Standard
Buffer Solution:
PBS
Metal Chelating Agents
Determined:
SDS-PAGE
Purity:
> 98%
Validated:
RP-HPLC
Sample Handling
Storage:
-20°C
Stability:
This bioreagent is stable at 4°C (short-term) and -70°C(long-term). After reconstitution, sample may be stored at 4°C for 2-7 days and below -18°C for future use.
Preparation:
Reconstitute in sterile distilled H2O to no less than 100ug/ml; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance.
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