Biomarkers
Kallikrein 22
Recombinant ID:
3442
Gene of Interest
Gene Synonyms:
Klk1b22;Klk-22;Klk22
Protein Names:
Kallikrein 1-related peptidase b22 (EC 3.4.21.35) (Beta-NGF-endopeptidase) (Epidermal growth factor-binding protein type A) (EGF-BP A) (Glandular kallikrein K22) (mGK-22) (Nerve growth factor beta chain endopeptidase) (Tissue kallikrein 22)
Accession Data
Organism:
Mus musculus (Mouse)
Mass (kDa):
28384
Length (aa):
259
Metal Binding:
Pending Verification
Proteomics (Proteome ID):
Kallikrein 1-related peptidase b22 (EC 3.4.21.35) (Beta-NGF-endopeptidase) (Epidermal growth factor-binding protein type A) (EGF-BP A) (Glandular kallikrein K22) (mGK-22) (Nerve growth factor beta chain endopeptidase) (Tissue kallikrein 22)
Proteomics (Chromosome):
UP000000589
Disease:
N/A
Mutagenesis:
N/A
Sequence:
MRFLILFLTLSLGGIDAAPPVQSRILGGFKCEKNSQPWQVAVYYLDEYLCGGVLLDRNWVLTAAHCYEDKYNIWLGKNKLFQDEPSAQHRLVSKSFPHPDFNMSLLQSVPTGADLSNDLMLLRLSKPADITDVVKPIDLPTTEPKLGSTCLASGWGSINQLIYQNPNDLQCVSIKLHPNEVCVKAHILKVTDVMLCAGEMNGGKDTCKGDSGGPLICDGVLQGITSWGSTPCGEPNAPAIYTKLIKFTSWIKDTMAKNP
Function [CC]:
Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin.
Analysis Summary:
Active site (3); Chain (1); Disulfide bond (5); Domain (1); Glycosylation (1); Propeptide (1); Signal peptide (1)
Reagent Data
Name:
Kallikrein 1-related peptidase b22 (EC 3.4.21.35) (Beta-NGF-endopeptidase) (Epidermal growth factor-binding protein type A) (EGF-BP A) (Glandular kallikrein K22) (mGK-22) (Nerve growth factor beta chain endopeptidase) (Tissue kallikrein 22)
Subcategory:
Recombinant
Source:
HEK293
Species:
Format:
Lyophilized
pH:
7.4-7.5
Formulation:
Sterile-filtered colorless solution
Formulation Concentration:
1mg/ml
Buffer Volume:
Standard
Buffer Solution:
PBS
Metal Chelating Agents
Determined:
SDS-PAGE
Purity:
> 98%
Validated:
RP-HPLC
Sample Handling
Storage:
-20°C
Stability:
This bioreagent is stable at 4°C (short-term) and -70°C(long-term). After reconstitution, sample may be stored at 4°C for 2-7 days and below -18°C for future use.
Preparation:
Reconstitute in sterile distilled H2O to no less than 100ug/ml; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance.
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