Biomarkers
ICAM-2
Recombinant ID:
3389
Gene of Interest
Gene Synonyms:
ICAM2
Protein Names:
Intercellular adhesion molecule 2 (ICAM-2) (CD antigen CD102)
Accession Data
Organism:
Homo sapiens (Human)
Mass (kDa):
30654
Length (aa):
275
Metal Binding:
Pending Verification
Proteomics (Proteome ID):
Intercellular adhesion molecule 2 (ICAM-2) (CD antigen CD102)
Proteomics (Chromosome):
UP000005640
Disease:
N/A
Mutagenesis:
N/A
Sequence:
MSSFGYRTLTVALFTLICCPGSDEKVFEVHVRPKKLAVEPKGSLEVNCSTTCNQPEVGGLETSLDKILLDEQAQWKHYLVSNISHDTVLQCHFTCSGKQESMNSNVSVYQPPRQVILTLQPTLVAVGKSFTIECRVPTVEPLDSLTLFLFRGNETLHYETFGKAAPAPQEATATFNSTADREDGHRNFSCLAVLDLMSRGGNIFHKHSAPKMLEIYEPVSDSQMVIIVTVVSVLLSLFVTSVLLCFIFGQHLRQQRMGTYGVRAAWRRLPQAFRP
Function [CC]:
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM2 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance.
Analysis Summary:
Beta strand (15); Chain (1); Disulfide bond (3); Domain (2); Glycosylation (6); Helix (3); Natural variant (3); Region (1); Sequence conflict (2); Signal peptide (1); Topological domain (2); Transmembrane (1)
Reagent Data
Name:
Intercellular adhesion molecule 2 (ICAM-2) (CD antigen CD102)
Subcategory:
Recombinant
Source:
HEK293
Species:
Format:
Lyophilized
pH:
7.4-7.5
Formulation:
Sterile-filtered colorless solution
Formulation Concentration:
1mg/ml
Buffer Volume:
Standard
Buffer Solution:
PBS
Metal Chelating Agents
Determined:
SDS-PAGE
Purity:
> 98%
Validated:
RP-HPLC
Sample Handling
Storage:
-20°C
Stability:
This bioreagent is stable at 4°C (short-term) and -70°C(long-term). After reconstitution, sample may be stored at 4°C for 2-7 days and below -18°C for future use.
Preparation:
Reconstitute in sterile distilled H2O to no less than 100ug/ml; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance.
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