Biomarkers
Ephrin-A4
Recombinant ID:
3328
Gene of Interest
Gene Synonyms:
EFNA4;EPLG4;LERK4
Protein Names:
Ephrin-A4 (EPH-related receptor tyrosine kinase ligand 4) (LERK-4)
Accession Data
Organism:
Homo sapiens (Human)
Mass (kDa):
22386
Length (aa):
201
Metal Binding:
Pending Verification
Proteomics (Proteome ID):
Ephrin-A4 (EPH-related receptor tyrosine kinase ligand 4) (LERK-4)
Proteomics (Chromosome):
UP000005640
Disease:
N/A
Mutagenesis:
N/A
Sequence:
MRLLPLLRTVLWAAFLGSPLRGGSSLRHVVYWNSSNPRLLRGDAVVELGLNDYLDIVCPHYEGPGPPEGPETFALYMVDWPGYESCQAEGPRAYKRWVCSLPFGHVQFSEKIQRFTPFSLGFEFLPGETYYYISVPTPESSGQCLRLQVSVCCKERKSESAHPVGSPGESGTSGWRGGDTPSPLCLLLLLLLLILRLLRIL
Function [CC]:
Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. May play a role in the interaction between activated B-lymphocytes and dendritic cells in tonsils.
Analysis Summary:
Alternative sequence (2); Chain (1); Disulfide bond (2); Domain (1); Glycosylation (1); Lipidation (1); Propeptide (1); Signal peptide (1); Expressed in the adult spleen, lymph node, prostate, ovary, small intestine, and colon, and in fetal heart, lung, liver and kidney. Also detected in hematopoietic cell lines.
Reagent Data
Name:
Ephrin-A4 (EPH-related receptor tyrosine kinase ligand 4) (LERK-4)
Subcategory:
Recombinant
Source:
HEK293
Species:
Format:
Lyophilized
pH:
7.4-7.5
Formulation:
Sterile-filtered colorless solution
Formulation Concentration:
1mg/ml
Buffer Volume:
Standard
Buffer Solution:
PBS
Metal Chelating Agents
Determined:
SDS-PAGE
Purity:
> 98%
Validated:
RP-HPLC
Sample Handling
Storage:
-20°C
Stability:
This bioreagent is stable at 4°C (short-term) and -70°C(long-term). After reconstitution, sample may be stored at 4°C for 2-7 days and below -18°C for future use.
Preparation:
Reconstitute in sterile distilled H2O to no less than 100ug/ml; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance.
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