Biomarkers
Carbonic Anhydrase XIV
Recombinant ID:
3207
Gene of Interest
Gene Synonyms:
CA14;UNQ690/PRO1335
Protein Names:
Carbonic anhydrase 14 (EC 4.2.1.1) (Carbonate dehydratase XIV) (Carbonic anhydrase XIV) (CA-XIV)
Accession Data
Organism:
Homo sapiens (Human)
Mass (kDa):
37668
Length (aa):
337
Metal Binding:
METAL 109 109 Zinc; catalytic. {ECO:0000269|PubMed:24374484}.; METAL 111 111 Zinc; catalytic. {ECO:0000269|PubMed:24374484}.; METAL 135 135 Zinc; catalytic. {ECO:0000269|PubMed:24374484}.
Proteomics (Proteome ID):
Carbonic anhydrase 14 (EC 4.2.1.1) (Carbonate dehydratase XIV) (Carbonic anhydrase XIV) (CA-XIV)
Proteomics (Chromosome):
UP000005640
Disease:
N/A
Mutagenesis:
N/A
Sequence:
MLFSALLLEVIWILAADGGQHWTYEGPHGQDHWPASYPECGNNAQSPIDIQTDSVTFDPDLPALQPHGYDQPGTEPLDLHNNGHTVQLSLPSTLYLGGLPRKYVAAQLHLHWGQKGSPGGSEHQINSEATFAELHIVHYDSDSYDSLSEAAERPQGLAVLGILIEVGETKNIAYEHILSHLHEVRHKDQKTSVPPFNLRELLPKQLGQYFRYNGSLTTPPCYQSVLWTVFYRRSQISMEQLEKLQGTLFSTEEEPSKLLVQNYRALQPLNQRMVFASFIQAGSSYTTGEMLSLGVGILVGCLCLLLAVYFIARKIRKKRLENRKSVVFTSAQATTEA
Function [CC]:
Reversible hydration of carbon dioxide.
Analysis Summary:
Active site (2); Beta strand (16); Chain (1); Disulfide bond (1); Domain (1); Glycosylation (1); Helix (9); Metal binding (3); Modified residue (1); Region (1); Sequence conflict (1); Signal peptide (1); Topological domain (2); Transmembrane (1); Turn (1); High expression in all parts of the central nervous system and lower expression in adult liver, heart, small intestine, colon, kidney, urinary bladder and skeletal muscle.
Reagent Data
Name:
Carbonic anhydrase 14 (EC 4.2.1.1) (Carbonate dehydratase XIV) (Carbonic anhydrase XIV) (CA-XIV)
Subcategory:
Recombinant
Source:
HEK293
Species:
Format:
Lyophilized
pH:
7.4-7.5
Formulation:
Sterile-filtered colorless solution
Formulation Concentration:
1mg/ml
Buffer Volume:
Standard
Buffer Solution:
PBS
Metal Chelating Agents
Determined:
SDS-PAGE
Purity:
> 98%
Validated:
RP-HPLC
Sample Handling
Storage:
-20°C
Stability:
This bioreagent is stable at 4°C (short-term) and -70°C(long-term). After reconstitution, sample may be stored at 4°C for 2-7 days and below -18°C for future use.
Preparation:
Reconstitute in sterile distilled H2O to no less than 100ug/ml; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance.
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