Biomarkers
Betacellulin
Recombinant ID:
3195
Gene of Interest
Gene Synonyms:
BTC
Protein Names:
Probetacellulin [Cleaved into: Betacellulin (BTC)]
Accession Data
Organism:
Homo sapiens (Human)
Mass (kDa):
19746
Length (aa):
178
Metal Binding:
Pending Verification
Proteomics (Proteome ID):
Probetacellulin [Cleaved into: Betacellulin (BTC)]
Proteomics (Chromosome):
UP000005640
Disease:
N/A
Mutagenesis:
N/A
Sequence:
MDRAARCSGASSLPLLLALALGLVILHCVVADGNSTRSPETNGLLCGDPEENCAATTTQSKRKGHFSRCPKQYKHYCIKGRCRFVVAEQTPSCVCDEGYIGARCERVDLFYLRGDRGQILVICLIAVMVVFIILVIGVCTCCHPLRKRRKRKKKEEEMETLGKDITPINEDIEETNIA
Function [CC]:
Growth factor that binds to EGFR, ERBB4 and other EGF receptor family members. Potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells. {ECO:0000269|PubMed:8570211}.
Analysis Summary:
Beta strand (4); Chain (2); Compositional bias (1); Disulfide bond (3); Domain (1); Glycosylation (1); Helix (1); Natural variant (3); Propeptide (1); Signal peptide (1); Topological domain (2); Transmembrane (1); Turn (2); Synthesized in several tissues and tumor cells. Predominantly expressed in pancreas and small intestine. {ECO:0000269|PubMed:8919026}.
Reagent Data
Name:
Probetacellulin [Cleaved into: Betacellulin (BTC)]
Subcategory:
Recombinant
Source:
HEK293
Species:
Format:
Lyophilized
pH:
7.4-7.5
Formulation:
Sterile-filtered colorless solution
Formulation Concentration:
1mg/ml
Buffer Volume:
Standard
Buffer Solution:
PBS
Metal Chelating Agents
Determined:
SDS-PAGE
Purity:
> 98%
Validated:
RP-HPLC
Sample Handling
Storage:
-20°C
Stability:
This bioreagent is stable at 4°C (short-term) and -70°C(long-term). After reconstitution, sample may be stored at 4°C for 2-7 days and below -18°C for future use.
Preparation:
Reconstitute in sterile distilled H2O to no less than 100ug/ml; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance.
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